Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ML-7 | selective MLCK inhibitor | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + myosin light chain | - |
Mus musculus | ADP + myosin light chain phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MLCK | - |
Mus musculus |
myosin light chain kinase | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | MLCK expression is significantly up-regulated after controlled cortical impact with a maximum 12 h post-injury | up |
General Information | Comment | Organism |
---|---|---|
physiological function | phosphorylation of myosin light chains by myosin light chain kinase activates endothelial contractile elements and results in a rearrangement of the cytoskeleton | Mus musculus |