Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | tumor necrosis factor-alpha induces enzyme activity in vivo | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ML-7 | - |
Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + light chain myosin II | Bos taurus | causes endothelial contraction | ADP + phosphorylated light chain myosin II | - |
? | |
additional information | Bos taurus | infection of brain endothelial cells with Haemophilus somnus causes alterations in brain endothelial cell and blood-brain barrier integrity and causes inflammation involving the enzyme, which acts in rapid cytoskeletal rearrangement, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Bos taurus | - |
brain endothelium cell line | a SV40-infected endothelial cell line | Bos taurus | - |
central nervous system | - |
Bos taurus | - |
endothelial cell | brain | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + light chain myosin II | - |
Bos taurus | ADP + phosphorylated light chain myosin II | - |
? | |
ATP + light chain myosin II | causes endothelial contraction | Bos taurus | ADP + phosphorylated light chain myosin II | - |
? | |
additional information | infection of brain endothelial cells with Haemophilus somnus causes alterations in brain endothelial cell and blood-brain barrier integrity and causes inflammation involving the enzyme, which acts in rapid cytoskeletal rearrangement, overview | Bos taurus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MLCK | - |
Bos taurus |
myosin light-chain kinase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Bos taurus |