Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ML-7 | specific inhibitor of MLCK, has a chemopreventive effect in an in vitro mouse mammary organ culture model, in vivo the inhibitor retards the growth of mammary tumours, acts as an adjuvant to etoposide stimulating its ability to prevent growth of established tomours, overview | Mus musculus | |
ML-7 | specific inhibitor of MLCK, in vivo the inhibitor retards the growth of prostate tumours, acts as an adjuvant to etoposide stimulating its ability to prevent growth of established tomours, overview | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | inhibition of the enzyme retards the growth of mammary cancer cells | ? | - |
? | |
additional information | Rattus norvegicus | inhibition of the enzyme retards the growth of prostate cancer cells | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Mat-Ly-Lu cell | a prostate cancer cell line | Rattus norvegicus | - |
Mm5MT cell | a mammary adenocarcinoma cell line | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | inhibition of the enzyme retards the growth of mammary cancer cells | Mus musculus | ? | - |
? | |
additional information | inhibition of the enzyme retards the growth of prostate cancer cells | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MLCK | - |
Mus musculus |
MLCK | - |
Rattus norvegicus |
myosin light chain kinase | - |
Mus musculus |
myosin light chain kinase | - |
Rattus norvegicus |