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Literature summary for 2.7.11.18 extracted from

  • Jinsart, W.; Ternai, B.; Polya, G.M.
    Inhibition and activation of wheat embryo calcium-dependent protein kinase and inhibition of avian myosin light chain kinase by long chain aliphatic amphiphiles (1991), Plant Sci., 78, 165-175.
No PubMed abstract available
Search for more literature for 2.7.11.18

Inhibitors

Inhibitors Comment Organism Structure
1,12-diaminododecane IC50: 0.063 mM Gallus gallus
1-hexadecylpyridinium bromide IC50: 0.049 mM Gallus gallus
acylcarnitin weak Gallus gallus
alkylamine long and straight chain, most effective with chain length C-13 to C-18 Gallus gallus
alkyltrimethylammonium halide
-
 Gallus gallus
D-sphingosine IC50: 0.006 mM Gallus gallus
decylamine IC50: 0.2 mM Gallus gallus
dihydrosphingosine erythro- and threo-dihydrosphingosine, IC50: 0.008 mM Gallus gallus
Dimethyldioctadecylammonium bromide IC50: 0.008 mM Gallus gallus
dioctylamine IC50: 0.055 mM Gallus gallus
dodecylamine IC50: 0.083 mM Gallus gallus
dodecyltrimethylammonium bromide IC50: 0.078 mM Gallus gallus
hexadecylamine IC50: 0.016 mM Gallus gallus
hexadecyltrimethylammonium bromide IC50: 0.011 mM Gallus gallus
lauroylcholine iodide IC50: 0.12 mM Gallus gallus
merocyanine dye (C16) IC50: 0.040 mM Gallus gallus
merocyanine dye (CH3)
-
 Gallus gallus
myristoylcarnitine chloride
-
 Gallus gallus
myristoylcholine iodide IC50: 0.02 mM Gallus gallus
N-Alkyl-N,N-dimethyl-3-ammonio-1-propanesulfonates zwittergents 3-14 and 16 Gallus gallus
N-methyloctadecylamine IC50: 0.01 mM Gallus gallus
Octadecylamine IC50: 0.011 mM Gallus gallus
oleylamine IC50: 0.006 mM Gallus gallus
palmitoylcarnitine chloride
-
 Gallus gallus
palmitoylcholine iodide IC50: 0.014 mM Gallus gallus
sodium alkylsulfate
-
 Gallus gallus
sodium dodecylsulfate IC50: 0.049 mM Gallus gallus
Sodium octadecylsulfate IC50: 0.043 mM Gallus gallus
Sodium tetradecylsulfate IC50: 0.038 mM Gallus gallus
stearoylcarnitine chloride
-
 Gallus gallus
stearoylcholine iodide IC50: 0.013 mM Gallus gallus
tetradecylamine IC50: 0.012 mM Gallus gallus
Tetradecyltrimethylammonium bromide IC50: 0.011 mM Gallus gallus
tridecylamine IC50: 0.019 mM Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myosin light chain Gallus gallus
-
 ADP + myosin light chain phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin light chain
-
 Gallus gallus ADP + myosin light chain phosphate
-
 ?

Cofactor

Cofactor Comment Organism Structure
Calmodulin requirement Gallus gallus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.006
-
 IC50: 0.006 mM Gallus gallus D-sphingosine
0.006
-
 IC50: 0.006 mM Gallus gallus oleylamine
0.008
-
 IC50: 0.008 mM Gallus gallus Dimethyldioctadecylammonium bromide
0.008
-
 erythro- and threo-dihydrosphingosine, IC50: 0.008 mM Gallus gallus dihydrosphingosine
0.01
-
 IC50: 0.01 mM Gallus gallus N-methyloctadecylamine
0.011
-
 IC50: 0.011 mM Gallus gallus hexadecyltrimethylammonium bromide
0.011
-
 IC50: 0.011 mM Gallus gallus Tetradecyltrimethylammonium bromide
0.011
-
 IC50: 0.011 mM Gallus gallus Octadecylamine
0.012
-
 IC50: 0.012 mM Gallus gallus tetradecylamine
0.013
-
 IC50: 0.013 mM Gallus gallus stearoylcholine iodide
0.014
-
 IC50: 0.014 mM Gallus gallus palmitoylcholine iodide
0.016
-
 IC50: 0.016 mM Gallus gallus hexadecylamine
0.019
-
 IC50: 0.019 mM Gallus gallus tridecylamine
0.02
-
 IC50: 0.02 mM Gallus gallus myristoylcholine iodide
0.038
-
 IC50: 0.038 mM Gallus gallus Sodium tetradecylsulfate
0.04
-
 IC50: 0.040 mM Gallus gallus merocyanine dye (C16)
0.043
-
 IC50: 0.043 mM Gallus gallus Sodium octadecylsulfate
0.049
-
 IC50: 0.049 mM Gallus gallus sodium dodecylsulfate
0.049
-
 IC50: 0.049 mM Gallus gallus 1-hexadecylpyridinium bromide
0.055
-
 IC50: 0.055 mM Gallus gallus dioctylamine
0.063
-
 IC50: 0.063 mM Gallus gallus 1,12-diaminododecane
0.078
-
 IC50: 0.078 mM Gallus gallus dodecyltrimethylammonium bromide
0.083
-
 IC50: 0.083 mM Gallus gallus dodecylamine
0.12
-
 IC50: 0.12 mM Gallus gallus lauroylcholine iodide
0.2
-
 IC50: 0.2 mM Gallus gallus decylamine