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Literature summary for 2.7.11.18 extracted from
- Primary structure required for the inhibition of smooth muscle myosin light chain kinase (1992), FEBS Lett., 312, 245-248.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AKKLSKDRMAAYMARRK | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo |  |
| AKKLSKDRMKKYMA | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo | |
| AKKLSKDRMKKYMAAAA | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo | |
| AKKLSKDRMKKYMARR | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo | |
| AKKLSKDRMKKYMARRK | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo | |
| AKKLSKDRMKKYMARRKWQKTG | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo | |
| KDRMKKYMARR | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo | |
| LSKDRMKKYMARRKWQK | synthetic peptide, analog of inhibitory region of myosin light chain kinase | Meleagris gallopavo | |
| additional information | structural requirements of autoinhibition of myosin light chain kinase | Meleagris gallopavo |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Meleagris gallopavo | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + myosin light chain | Meleagris gallopavo | - |
ADP + myosin light chain phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Meleagris gallopavo | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| gizzard | - |
Meleagris gallopavo | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + myosin light chain | - |
Meleagris gallopavo | ADP + myosin light chain phosphate | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Calmodulin | requirement | Meleagris gallopavo | |
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Release 2023.1 (January 2023)
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