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Literature summary for 2.7.11.17 extracted from

  • Sierra, A.; Zhu, Z.; Sapay, N.; Sharotri, V.; Kline, C.F.; Luczak, E.D.; Subbotina, E.; Sivaprasadarao, A.; Snyder, P.M.; Mohler, P.J.; Anderson, M.E.; Vivaudou, M.; Zingman, L.V.; Hodgson-Zingman, D.M.
    Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II (2013), J. Biol. Chem., 288, 1568-1581.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + Kir6.2 subunit of cardiac ATP-sensitive potassium channel Mus musculus phosphorylation of Kir6.2 subunit of cardiac ATP-sensitive potassium channel promotes endocytosis of cardiac ATP-sensitive potassium channels ADP + phosphorylated Kir6.2 subunit of cardiac ATP-sensitive potassium channel
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Kir6.2 subunit of cardiac ATP-sensitive potassium channel
-
 Mus musculus ADP + phosphorylated Kir6.2 subunit of cardiac ATP-sensitive potassium channel
-
 ?
ATP + Kir6.2 subunit of cardiac ATP-sensitive potassium channel phosphorylation of Kir6.2 subunit of cardiac ATP-sensitive potassium channel promotes endocytosis of cardiac ATP-sensitive potassium channels Mus musculus ADP + phosphorylated Kir6.2 subunit of cardiac ATP-sensitive potassium channel
-
 ?

Synonyms

Synonyms Comment Organism
CaMKII
-
 Mus musculus

General Information

General Information Comment Organism
physiological function phosphorylation of Kir6.2 subunit of cardiac ATP-sensitive potassium channels promotes endocytosis of cardiac ATP-sensitive potassium channels. This mechanism couples the surface expression of cardiac ATP-sensitive potassium channel with calcium signaling Mus musculus