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Literature summary for 2.7.11.17 extracted from

  • Takemoto-Kimura, S.; Terai, H.; Takamoto, M.; Ohmae, S.; Kikumura, S.; Segi, E.; Arakawa, Y.; Furuyashiki, T.; Narumiya, S.; Bito, H.
    Molecular cloning and characterization of CLICK-III/CaMKIg, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK) (2003), J. Biol. Chem., 278, 18597-18605.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Calmodulin dependent on, the Ca2+/calmodulin-binding domain overlaps with the autoinhibition domain Homo sapiens
Calmodulin dependent on, the Ca2+/calmodulin-binding domain overlaps with the autoinhibition domain Mus musculus
additional information Thr178 is localized in the activation loop Homo sapiens
additional information Thr178 is localized in the activation loop Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
CaMKIgamma, DNA and amino acid sequence determination and analysis, expression as GFT-tagged protein in COS-7 cells with localization in the Golgi apparatus and the plasma membrane Mus musculus
CaMKIgamma, DNA and amino acid sequence determination and analysis, expression in COS-7 cells Homo sapiens
expression of CaMKIalpha in COS-7 cells with localization in the Golgi apparatus and the plasma membrane Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
additional information the Ca2+/calmodulin-binding domain overlaps with the autoinhibition domain Homo sapiens
additional information the Ca2+/calmodulin-binding domain overlaps with the autoinhibition domain Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi membrane
-
Mus musculus 139
-
membrane anchored Homo sapiens 16020
-
membrane anchored Mus musculus 16020
-
plasma membrane
-
Mus musculus 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on, activates, the Ca2+/calmodulin-binding domain overlaps with the autoinhibition domain Homo sapiens
Ca2+ dependent on, activates, the Ca2+/calmodulin-binding domain overlaps with the autoinhibition domain Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens Q96NX5 CaMKIgamma; isozyme CaMKIgamma or CLICK-III
-
Mus musculus Q91VB2 CaMKIgamma
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
brain isozyme CaMKIgamma, high expression level Homo sapiens
-
brain isozyme CaMKIgamma, high expression level Mus musculus
-
hippocampus
-
Homo sapiens
-
hippocampus
-
Mus musculus
-
neuron CA1 and CA3 hippocampal neurons Homo sapiens
-
neuron CA1 and CA3 hippocampal neurons Mus musculus
-

Synonyms

Synonyms Comment Organism
calcium/calmodulin-dependent protein kinase 1G
-
Homo sapiens
calcium/calmodulin-dependent protein kinase 1G
-
Mus musculus
CaM kinase IG
-
Homo sapiens
CaM kinase IG
-
Mus musculus
CaMK-like CREB kinase-III
-
Homo sapiens
CaMK-like CREB kinase-III
-
Mus musculus
CaMKIalpha
-
Rattus norvegicus
CaMKIG
-
Homo sapiens
CaMKIG
-
Mus musculus
CaMKIgamma
-
Homo sapiens
CaMKIgamma
-
Mus musculus
CLICK-III
-
Homo sapiens
CLICK-III
-
Mus musculus
More CLICK-III belongs to the CaMKI family Homo sapiens
More CLICK-III belongs to the CaMKI family Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens
ATP
-
Mus musculus