Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | requirement | Gallus gallus | |
Ca2+ | requirement | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
141000 | - |
x * 141000, SDS-PAGE | Gallus gallus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + caldesmon | Bos taurus | - |
ADP + caldesmon phosphate | - |
? | |
ATP + caldesmon | Gallus gallus | caldesmon plays a role in the regulation of smooth muscle contraction | ADP + caldesmon phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Gallus gallus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Gallus gallus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate | the reaction is an intramolecular autophosphorylation which is site-specific: predominantly serine with some threonine and no tyrosine residues are phosphorylated | Gallus gallus | |
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate | the reaction is an intramolecular autophosphorylation which is site-specific: predominantly serine with some threonine and no tyrosine residues are phosphorylated | Bos taurus | |
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate | enzyme appears to be identical with caldesmon | Gallus gallus | |
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate | enzyme appears to be identical with caldesmon | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Bos taurus | - |
gizzard | smooth muscle | Gallus gallus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00027 | - |
histone III-S | Gallus gallus |
0.00054 | - |
aortic caldesmon | Gallus gallus |
0.00063 | - |
synapsin | Gallus gallus |
0.00073 | - |
autophosphorylation | Gallus gallus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + caldesmon | - |
Gallus gallus | ADP + caldesmon phosphate | - |
r | |
ATP + caldesmon | - |
Bos taurus | ADP + caldesmon phosphate | - |
? | |
ATP + caldesmon | caldesmon plays a role in the regulation of smooth muscle contraction | Gallus gallus | ADP + caldesmon phosphate | - |
? | |
ATP + casein | - |
Gallus gallus | ADP + phosphocasein | - |
? | |
ATP + histone | histone V-S | Bos taurus | ADP + phosphohistone | - |
? | |
ATP + histone | calf thymus histone II-S, poor substrate | Gallus gallus | ADP + phosphohistone | - |
? | |
ATP + histone | histone III-S | Gallus gallus | ADP + phosphohistone | - |
? | |
ATP + histone | histone III-S | Bos taurus | ADP + phosphohistone | - |
? | |
ATP + myosin | - |
Bos taurus | ADP + phosphomyosin | - |
? | |
ATP + myosin | isolated light chain of smooth-muscle myosin, phosphorylated at 80% the rate of caldesmon | Gallus gallus | ADP + phosphomyosin | - |
? | |
ATP + synapsin | - |
Bos taurus | ADP + phosphosynapsin | - |
? | |
ATP + synapsin | brain synapsin best substrate of chicken gizzard caldesmon kinase | Gallus gallus | ADP + phosphosynapsin | - |
? | |
additional information | no substrates are bovine cardiac C-protein, bovine brain fodrin, rabbit skeletal muscle glycogen synthase, phosphorylase B, troponon (I + T + C), actin, tropomyosin, smooth muscle actin, filamin, vinculin, alpha-actinin, protamine or phosvitin | Gallus gallus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 141000, SDS-PAGE | Gallus gallus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | requirement | Gallus gallus | |
Calmodulin | requirement | Bos taurus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Gallus gallus | isoelectric focusing, multiple charge-variants | 5.9 | 5.78 |
Bos taurus | isoelectric focusing, multiple charge-variants | 5.9 | 5.78 |