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Literature summary for 2.7.11.17 extracted from

  • Hunter, T.
    Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling (1995), Cell, 80, 225-236.
    View publication on PubMed
Search for more literature for 2.7.11.17

Activating Compound

Activating Compound Comment Organism Structure
additional information Ras activity can be induced by the nuclear growth factor eukaryota

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ binding required for activity eukaryota

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein eukaryota
-
 ADP + a phosphoprotein
-
 ?
additional information eukaryota protein kinases and protein phosphatases regulate enzyme activities in the cell, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
eukaryota
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
 eukaryota ADP + a phosphoprotein
-
 ?
ATP + cAMP-response element-binding protein i.e. CREB, phosphorylation at S133, substrate of CaMKIV and CaMKII eukaryota ADP + phosphorylated cAMP-response element-binding protein
-
 ?
ATP + glycogen synthase
-
 eukaryota ADP + phosphorylated glycogen synthase
-
 ?
additional information protein kinases and protein phosphatases regulate enzyme activities in the cell, overview eukaryota ?
-
 ?

Synonyms

Synonyms Comment Organism
Ca2+-CaM-dependent protein kinase II
-
 eukaryota
CaMKII
-
 eukaryota

Cofactor

Cofactor Comment Organism Structure
ATP
-
 eukaryota
Calmodulin binding required for activity eukaryota