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Literature summary for 2.7.11.16 extracted from

  • Chakraborty, P.K.; Zhang, Y.; Coomes, A.S.; Kim, W.J.; Stupay, R.; Lynch, L.D.; Atkinson, T.; Kim, J.I.; Nie, Z.; Daaka, Y.
    G protein-coupled receptor kinase GRK5 phosphorylates moesin and regulates metastasis in prostate cancer (2014), Cancer Res., 74, 3489-3500.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + moesin Homo sapiens phosphorylation at Thr66 ADP + phosphorylated moesin
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P34947
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-
PC-3 cell
-
 Homo sapiens
-
prostate cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + moesin phosphorylation at Thr66 Homo sapiens ADP + phosphorylated moesin
-
 ?

Synonyms

Synonyms Comment Organism
G protein-coupled receptor kinase 5
-
 Homo sapiens
GRK5
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme regulates migration and invasion of prostate cancer cells Homo sapiens