Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [beta-adrenergic receptor] | Mus musculus | - |
ADP + phospho-[beta-adrenergic receptor] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [beta-adrenergic receptor] | - |
Mus musculus | ADP + phospho-[beta-adrenergic receptor] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
G protein-coupled receptor kinase 2 | - |
Mus musculus |
GRK2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme ablation leads to marked vascular malformations involving impaired recruitment of mural cells. Enzyme downregulation is a relevant event in the tumoral angiogenic switch | Mus musculus |
physiological function | G protein-coupled receptor kinase 2 is a key angiogenesis regulator | Mus musculus |