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Literature summary for 2.7.11.15 extracted from

  • Loniewski, K.; Shi, Y.; Pestka, J.; Parameswaran, N.
    Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages (2008), Mol. Immunol., 45, 2312-2322.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information activation of Toll-like receptors significantly increases GRK2 expression in primary macrophages, mechanism, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus G protein-coupled receptors and Toll-like receptors play a crucial role in the regulation of macrophage biology and innate immunity, overview ?
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?
additional information Mus musculus C57BL/6 G protein-coupled receptors and Toll-like receptors play a crucial role in the regulation of macrophage biology and innate immunity, overview ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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C57BL/six mice
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Mus musculus C57BL/6
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C57BL/six mice
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Source Tissue

Source Tissue Comment Organism Textmining
macrophage peritoneal macrophages, activation of Toll-like receptors significantly increases GRK2 expression in primary macrophages, mechanism, overview Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information G protein-coupled receptors and Toll-like receptors play a crucial role in the regulation of macrophage biology and innate immunity, overview Mus musculus ?
-
?
additional information G protein-coupled receptors and Toll-like receptors play a crucial role in the regulation of macrophage biology and innate immunity, overview Mus musculus C57BL/6 ?
-
?

Synonyms

Synonyms Comment Organism
G-protein coupled receptor kinase 2
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Mus musculus
GRK2
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Mus musculus