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Literature summary for 2.7.11.15 extracted from
- Decreased expression of G-protein coupled receptor kinase 2 in cold thyroid nodules (2005), Exp. Clin. Endocrinol. Diabetes, 113, 102-106.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
| membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [TSH receptor] | Homo sapiens | GRK2 and GRK3, receptor activation | ADP + [TSH receptor]phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thyroid nodule | prepared without lymphocytic infiltrations in the tumor, GRKs expression patterns, low expression of GRK2, and high expression level of GRK3 | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [TSH receptor] | GRK2 and GRK3, receptor activation | Homo sapiens | ADP + [TSH receptor]phosphate | - |
? | |
| ATP + [TSH receptor] | GRK2 and GRK3 | Homo sapiens | ADP + [TSH receptor]phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| G-protein coupled receptor kinase 2 | - |
Homo sapiens |
| GRK2 | - |
Homo sapiens |
| GRK3 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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