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Literature summary for 2.7.11.14 extracted from

  • Zhang, H.; Li, S.; Doan, T.; Rieke, F.; Detwiler, P.B.; Frederick, J.M.; Baehr, W.
    Deletion of PrBP/delta impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments (2007), Proc. Natl. Acad. Sci. USA, 104, 8857-8862.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus absence of PrBP/delta, a ubiquitous prenyl binding protein, in Pde6d knockout mice retina impairs transport of prenylated proteins, particularly GRK1 and cone PDE, to rod and cone outer segments, resulting in altered photoreceptor physiology and a phenotype of a slowly progressing rod/cone dystrophy, overview ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Posttranslational Modification

Posttranslational Modification Comment Organism
lipoprotein the enzyme is farnesylated Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
eye
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 Mus musculus
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retina in rod outer segments Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information absence of PrBP/delta, a ubiquitous prenyl binding protein, in Pde6d knockout mice retina impairs transport of prenylated proteins, particularly GRK1 and cone PDE, to rod and cone outer segments, resulting in altered photoreceptor physiology and a phenotype of a slowly progressing rod/cone dystrophy, overview Mus musculus ?
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 ?

Synonyms

Synonyms Comment Organism
GRK1
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 Mus musculus