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Literature summary for 2.7.11.14 extracted from
- Recoverin and rhodopsin kinase activity in detergent-resistant membrane rafts from rod outer segments (2004), J. Biol. Chem., 279, 48647-48653.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | influence of complexing lipids on the activity of the solubilized enzyme | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | influence of complexing lipids on the activity of the solubilized enzyme, cholesterol increases the inhibition by recoverin by facilitating the binding | Bos taurus | |
| recoverin | inhibits the enzyme Ca2+-dependently in detergent-resistant membranes, that are insoluble in Triton X-100, cholesterol increases the inhibition by recoverin by facilitating the binding | Bos taurus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| photoreceptor outer segment membrane | - |
Bos taurus | 42622 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on, rhodopsin phosphorylation in rod outer segment membranes | Bos taurus |  |
| Mg2+ | - |
Bos taurus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + rhodopsin | Bos taurus | - |
ADP + phosphorhodopsin | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partially by isolation of the rod outer segment membrane, partial solubilization by Triton X-100 in presence of Ca2+ | Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| photoreceptor | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + rhodopsin | - |
Bos taurus | ADP + phosphorhodopsin | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Bos taurus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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