Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.14 extracted from

  • Kim, Y.H.; Kim, Y.S.; Noh, H.S.; Kang, S.S.; Cheon, E.W.; Park, S.K.; Lee, B.J.; Choi, W.S.; Cho, G.J.
    Changes in rhodopsin kinase and transducin in the rat retina in early-stage diabetes (2005), Exp. Eye Res., 80, 753-760.
    View publication on PubMed
Search for more literature for 2.7.11.14

Inhibitors

Inhibitors Comment Organism Structure
recoverin inhibits the enzyme, recoverin expression is reduced in diabetic rat retina Rattus norvegicus
Transducin inhibits the enzyme, recoverin expression is reduced in diabetic rat retina Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + rhodopsin Rattus norvegicus activity is increased in diabetes due to upregulation of the enzyme and downregulation of inhibitory recoverin and transducin ADP + phosphorhodopsin
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 healthy and diabetic Sprague-Dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
photoreceptor
-
 Rattus norvegicus
-
retina of healthy and diabetic Sprague-Dawley rats, expression of the enzyme is increased in the diabetic retina Rattus norvegicus
-
retinal rod outer segment Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + rhodopsin
-
 Rattus norvegicus ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin activity is increased in diabetes due to upregulation of the enzyme and downregulation of inhibitory recoverin and transducin Rattus norvegicus ADP + phosphorhodopsin
-
 ?

Synonyms

Synonyms Comment Organism
RK
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus