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Literature summary for 2.7.11.14 extracted from

  • Satpaev, D.K.; Chen, C.K.; Scotti, A.; Simon, M.I.; Hurley, J.B.; Slepak, V.Z.
    Autophosphorylation and ADP regulate the Ca2+-dependent interaction of recoverin with rhodopsin kinase (1998), Biochemistry, 37, 10256-10262.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
Calmodulin very poor inhibitor Bos taurus
recoverin Ca2+-dependent inhibition; Ca2+ is required for recoverin to bind RK, 0.1 mM ADP enhances, ATP causes RK autophosphorylation and strongly weakens inhibition, effect of N-myristoylation of recoverin on inhibition Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
66000
-
 x * 66000 Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + rhodopsin Bos taurus
-
 ADP + phosphorhodopsin
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein enzyme is autophosphorylated Bos taurus

Purification (Commentary)

Purification (Comment) Organism
recombinant RK expressed in SF9 cells Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + rhodopsin
-
 Bos taurus ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin highly specific for photobleached rhodopsin Bos taurus ADP + phosphorhodopsin
-
 ?

Subunits

Subunits Comment Organism
? x * 66000 Bos taurus