Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ALSTER | psi pyruvate dehydrogenase kinase peptide, selective inhibitor of deltaPKC-mediated pyruvate dehydrogenase kinase phosphorylation | Rattus norvegicus | |
YGRKKRRQRRR-GSG-ALSTER | psi pyruvate dehydrogenase kinase 1 peptide, inhibits the phosphorylation of pyruvate dehydrogenase kinase but not the phosphorylation of HSP, MARCKS, STAT, GAPDH, and troponin I | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate dehydrogenase kinase | Rattus norvegicus | - |
ADP + phosphorylated pyruvate dehydrogenase kinase | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P09215 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate dehydrogenase kinase | - |
Rattus norvegicus | ADP + phosphorylated pyruvate dehydrogenase kinase | - |
? |
Synonyms | Comment | Organism |
---|---|---|
delta protein kinase C | - |
Rattus norvegicus |
deltaPKC | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | pyruvate dehydrogenase kinase phosphorylation alone is critical for delta protein kinase C mediated injury by heart attack | Rattus norvegicus |