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Literature summary for 2.7.11.13 extracted from

  • Holmgren, C.; Cornmark, L.; Lonne, G.K.; Masoumi, K.C.; Larsson, C.
    Molecular characterization of protein kinase C delta (PKCdelta)-Smac interactions (2016), BMC Biochem., 17, 11 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
GF109203X
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q05655
-
-

Synonyms

Synonyms Comment Organism
PKCdelta
-
 Homo sapiens
protein kinase C delta
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function protein kinase C delta is an important regulator of apoptosis. PKCdelta binds directly to the pro-apoptotic protein Smac through its regulatory domain. The PKCdelta-Smac complex dissociates during induction of apoptosis Homo sapiens