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Literature summary for 2.7.11.13 extracted from

  • Kawakami, Y.; Nishimoto, H.; Kitaura, J.; Maeda-Yamamoto, M.; Kato, R.M.; Littman, D.R.; Rawlings, D.J.; Kawakami, T.
    Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion (2004), J. Biol. Chem., 279, 47720-47725.
    View publication on PubMed
Search for more literature for 2.7.11.13

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + Akt Mus musculus phosphorylation by PKC isozymes at Ser473, regulation of the phosphorylation activity by PKCbetaII in mast cells stimulated by stem cell factor or interaleukin-3, and in serum-stimulated fibroblasts, and in antigen-receptor stimulated T- or B-lymphocytes, overview ADP + phosphorylated Akt
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 several isozymes
-

Source Tissue

Source Tissue Comment Organism Textmining
B-lymphocyte
-
 Mus musculus
-
bone marrow
-
 Mus musculus
-
commercial preparation recombinant isozymes Mus musculus
-
fibroblast
-
 Mus musculus
-
hepatocyte from fetal liver Mus musculus
-
mast cell derived from bone marrow Mus musculus
-
T-lymphocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Akt phosphorylation by PKC isozymes at Ser473, regulation of the phosphorylation activity by PKCbetaII in mast cells stimulated by stem cell factor or interaleukin-3, and in serum-stimulated fibroblasts, and in antigen-receptor stimulated T- or B-lymphocytes, overview Mus musculus ADP + phosphorylated Akt
-
 ?
ATP + Akt Akt substrate is protein kinase B, phosphorylation by PKC isozymes at Ser473 involving phorbol esters Mus musculus ADP + phosphorylated Akt
-
 ?

Synonyms

Synonyms Comment Organism
PKC
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus