Activating Compound | Comment | Organism | Structure |
---|---|---|---|
gastrin | physiological activator of PKD2 in human AGS-B cells stably transfected with the CCK(B)/gastrin receptor | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
105000 | - |
x * 105000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9BZL6 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | phorbol 12,13-dibutyrate in the presence of dioleoylphosphatidylserine stimulates the autophosphorylation of PKD2 in a synergistic fashion. Phorbol esters also stimulate autophosphorylation of PKD2 in intact cells, C-terminal Ser876 is an in vivo phosphorylation site within PKD2 that is correlated with the activation status of the kinase | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
AGS cell | AGS-B cell | Homo sapiens | - |
HL-60 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + histone H1 | PKD2 activated by phorbol esters efficiently phosphorylate the exogenous substrate histone H1 | Homo sapiens | ADP + phosphorylated histone H1 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 105000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PKD2 | - |
Homo sapiens |
protein kinase C, D2 type | - |
Homo sapiens |
protein kinase D2 | - |
Homo sapiens |