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Literature summary for 2.7.11.12 extracted from

  • Govindasamy, K.; Jebiwott, S.; Jaijyan, D.K.; Davidow, A.; Ojo, K.K.; Van Voorhis, W.C.; Brochet, M.; Billker, O.; Bhanot, P.
    Invasion of hepatocytes by Plasmodium sporozoites requires cGMP-dependent protein kinase and calcium dependent protein kinase 4 (2016), Mol. Microbiol., 102, 349-363.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + TRAP protein Plasmodium berghei
-
ADP + phosphorylated TRAP protein
-
?

Organism

Organism UniProt Comment Textmining
Plasmodium berghei
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sporozoite
-
Plasmodium berghei
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + TRAP protein
-
Plasmodium berghei ADP + phosphorylated TRAP protein
-
?

Synonyms

Synonyms Comment Organism
PKG
-
Plasmodium berghei

General Information

General Information Comment Organism
malfunction enzyme inhibition decreases parasite egress from hepatocytes by inhibiting either the formation or release of merosomes Plasmodium berghei
physiological function the enzyme is required for sporozoite motility, invasion and merosome formation Plasmodium berghei