Literature summary for 2.7.11.12 extracted from

Zhu, M.; Yao, X.; Wu, M.; Qian, H.; Wu, Y.; Chen, Y.
Type II cGMP-dependent protein kinase directly inhibits HER2 activation of gastric cancer cells (2016), Mol. Med. Rep., 13, 1909-1913.

Search for more literature for 2.7.11.12

Activating Compound

Activating Compound	Comment	Organism	Structure
8-(4-chlorophenylthio)guanosine-3',5'-cyclic monophosphate	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + HER2 protein	Homo sapiens	phosphorylation at threonine 686	ADP + phosphorylated HER2 protein	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HGC-27 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + HER2 protein	phosphorylation at threonine 686	Homo sapiens	ADP + phosphorylated HER2 protein	-	?

Synonyms

Synonyms	Comment	Organism
PKG II	-	Homo sapiens
Type II cGMP-dependent protein kinase	-	Homo sapiens
type II cyclic guanosine monophosphate-dependent protein kinase	-	Homo sapiens

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Release 2023.1 (January 2023)