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Literature summary for 2.7.11.12 extracted from

  • Reger, A.S.; Yang, M.P.; Koide-Yoshida, S.; Guo, E.; Mehta, S.; Yuasa, K.; Liu, A.; Casteel, D.E.; Kim, C.
    Crystal structure of the cGMP-dependent protein kinase II leucine zipper and Rab11b protein complex reveals molecular details of G-kinase-specific interactions (2014), J. Biol. Chem., 289, 25393-25403.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with Rab11 protein, vapor diffusion method, using 0.056 M sodium phosphate monobasic monohydrate, 1.344 M potassium phosphate dibasic (pH 8.2), and 10 mM EDTA Homo sapiens

Protein Variants

Protein Variants Comment Organism
T62E/A66Q inactive Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + Rab11 protein Homo sapiens
-
 ADP + phosphorylated Rab11 protein
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q13237
-
-

Purification (Commentary)

Purification (Comment) Organism
IMAC nickel column chromatography and Superdex 75 gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Rab11 protein
-
 Homo sapiens ADP + phosphorylated Rab11 protein
-
 ?

Synonyms

Synonyms Comment Organism
cGMP-dependent protein kinase II
-
 Homo sapiens
PGK II
-
 Homo sapiens