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Literature summary for 2.7.11.12 extracted from

  • Waldkirch, E.; Uckert, S.; Sigl, K.; Imkamp, F.; Langnaese, K.; Richter, K.; Jonas, U.; Sohn, M.; Stief, C.; Wolf, G.; Hedlund, P.
    Expression and distribution of cyclic GMP-dependent protein kinase-1 isoforms in human penile erectile tissue (2008), J. Sex Med., 5, 536-543.
    View publication on PubMed

Application

Application Comment Organism
medicine downregulation of cyclic GMP-dependent protein kinase-1 alpha is linked to erectile dysfunction and diabetis mellitus Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
76000
-
isozyme cGKI alpha, SDS-PAGE Homo sapiens
78000
-
isozyme cGKI beta, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q13976
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cavernous artery
-
Homo sapiens
-
corpus cavernosum
-
Homo sapiens
-
corpus cavernosum penis
-
Homo sapiens
-
endothelium
-
Homo sapiens
-
HAC cell
-
Homo sapiens
-
hepatoma cell
-
Homo sapiens
-
smooth muscle cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
cGKI alpha isozyme Homo sapiens
cGKI beta isozyme Homo sapiens
cyclic GMP-dependent protein kinase-1
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
cGMP dependent Homo sapiens