Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-Br-cGMP | - |
Homo sapiens | |
cGMP | dependent on | Homo sapiens | |
additional information | NO, from NO donor sodium nitroprusside, induces cGMP production and thus increases enzyme activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
KT5823 | specific PKG inhibitor | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | NO induces enzyme activity responsible for modulation/inhibition of voltage-gated CaV1 and CaV2.2, i.e. L- and N-type, Ca2+ channels in neuroblastoma cells, in cardiovascular and smooth muscle cells Ca2+ channel activity is inhibited by direct nitrosylation of the channel proteins by NO, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
IMR-32 cell | neuroblastoma cell line | Homo sapiens | - |
neuroblastoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | NO induces enzyme activity responsible for modulation/inhibition of voltage-gated CaV1 and CaV2.2, i.e. L- and N-type, Ca2+ channels in neuroblastoma cells, in cardiovascular and smooth muscle cells Ca2+ channel activity is inhibited by direct nitrosylation of the channel proteins by NO, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKG | - |
Homo sapiens |