Literature summary for 2.7.11.12 extracted from

Yamamoto, T.; Suzuki, N.
Expression and function of cGMP-dependent protein kinase type I during medaka fish embryogenesis (2005), J. Biol. Chem., 280, 16979-16986.

Search for more literature for 2.7.11.12

Activating Compound

Activating Compound	Comment	Organism	Structure
cGMP	dependent on	Oryzias latipes

Cloned(Commentary)

Cloned (Comment)	Organism
DNA sequence determination and analysis, expression in NG108-15 hybrid cells constructed of mouseneuroblastoma cell line N18TG-2 and rat glioma cell line C6BU-1	Oryzias latipes

Protein Variants

Protein Variants	Comment	Organism
additional information	injection of PKG-Ialpha-specific antisense or overexpression constructs into two-cell stage embryos causes severe abnormalities in the developing embryos, phenotypes, overview	Oryzias latipes
additional information	injection of PKG-Ibeta-specific antisense or overexpression constructs into two-cell stage embryos causes severe abnormalities in the developing embryos, phenotypes, overview	Oryzias latipes

Inhibitors

Inhibitors	Comment	Organism	Structure
KT5823	PKG inhibitor; PKG inhibitor	Oryzias latipes

Organism

Organism	UniProt	Comment	Textmining
Oryzias latipes	Q75PY3	PKG Ibeta; makada fish, enzyme form PKG I in two iszymes alpha and beta	-
Oryzias latipes	Q75PY4	PKG Ialpha; makada fish, enzyme form PKG I in two iszymes alpha and beta	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
auditory vesicle	embryonal, high expression of isozyme PKGIbeta	Oryzias latipes	-
embryo	expression of both PKGIalpha and PKGIbeta after late gastrula stage	Oryzias latipes	-
gill arch	embryonal, high expression of isozyme PKGIalpha	Oryzias latipes	-
spinal cord	embryonal, high expression of isozyme PKGIalpha	Oryzias latipes	-

Synonyms

Synonyms	Comment	Organism
PKG I	-	Oryzias latipes

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Release 2023.1 (January 2023)