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Literature summary for 2.7.11.12 extracted from

  • Oster, H.; Werner, C.; Magnone, M.C.; Mayser, H.; Feil, R.; Seeliger, M.W.; Hofmann, F.; Albrecht, U.
    cGMP-dependent protein kinase II modulates mPer1 and mPer2 gene induction and influences phase shifts of the circadian clock (2003), Curr. Biol., 13, 725-733.
    View publication on PubMed
Search for more literature for 2.7.11.12

Protein Variants

Protein Variants Comment Organism
additional information PKGII-deficient mice are defective in renal functiona regulation, and in resetting the circadian clock because light induction of mPer2 gene in the hypothalamus is strongly reduced in the early peroid of the night, whereas mPer1 gene induction is elevated Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus PKGII modulates mPer1 and mPer2 gene induction, not by phosphorylation of CREB at Ser133, and influences phase shifts of the circadian clock, regulation model, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
hypothalamus
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 Mus musculus
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suprachiasmatic nucleus of the hypothalamus Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PKGII modulates mPer1 and mPer2 gene induction, not by phosphorylation of CREB at Ser133, and influences phase shifts of the circadian clock, regulation model, overview Mus musculus ?
-
 ?
additional information no activity with the cAMP-responsive element binding protein, i.e. CREB Mus musculus ?
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 ?

Synonyms

Synonyms Comment Organism
cGKII
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 Mus musculus
cGMP-dependent protein kinase II
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 Mus musculus
PKGII
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 Mus musculus