Literature summary for 2.7.11.11 extracted from

Kurokawa, H.; Kato, K.; Iwanaga, T.; Sugi, T.; Sudo, A.; Kobayashi, K.; Gong, H.; Takemae, H.; Recuenco, F.C.; Horimoto, T.; Akashi, H.
Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth (2011), PLoS ONE, 6, e22492.

Search for more literature for 2.7.11.11

Cloned(Commentary)

Cloned (Comment)	Organism
expression of the TgPKA catalytic subunit as GST-tagged protein in the wheat germ cell-free protein synthesis system	Toxoplasma gondii

Inhibitors

Inhibitors	Comment	Organism	Structure
inhibitor H89	ATP competitive chemical inhibitor H89	Toxoplasma gondii
protein kinase inhibitor	natural peptide inhibitor PKI from Bos taurus	Toxoplasma gondii

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
69000	-	x * 69000, recombinant GST-tagged TgPKA catalytic subunit, SDS-PAGE	Toxoplasma gondii

Organism

Organism	UniProt	Comment	Textmining
Toxoplasma gondii	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	autophosphorylation of PKA catalytic subunit is necessary for its enzymatic activation and interaction with PKA regulatory subunits	Toxoplasma gondii

Purification (Commentary)

Purification (Comment)	Organism
recombinant GST-tagged TgPKA catalytic subunit from wheat germ cell-free protein synthesis system by glutathione affinity chromatography	Toxoplasma gondii

Source Tissue

Source Tissue	Comment	Organism	Textmining
tachyzoite	-	Toxoplasma gondii	-

Subunits

Subunits	Comment	Organism
?	x * 69000, recombinant GST-tagged TgPKA catalytic subunit, SDS-PAGE	Toxoplasma gondii

Synonyms

Synonyms	Comment	Organism
cAMP dependent protein kinase	-	Toxoplasma gondii
PKA	-	Toxoplasma gondii

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Toxoplasma gondii

General Information

General Information	Comment	Organism
physiological function	PKA plays an important role in the growth of tachyzoites	Toxoplasma gondii

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Release 2023.1 (January 2023)