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Literature summary for 2.7.11.11 extracted from

  • Bardales, J.R.; Cascallana, J.L.; Villamarin, A.
    Differential distribution of cAMP-dependent protein kinase isoforms in various tissues of the bivalve mollusc Mytilus galloprovincialis (2011), Acta Histochem., 113, 743-748.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cilium isozyme PKAmyt2 is the only isoform detected in the cilia of gill filaments Mytilus galloprovincialis 5929
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cytoplasm isozyme PKAmyt1 Mytilus galloprovincialis 5737
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Organism

Organism UniProt Comment Textmining
Mytilus galloprovincialis
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two isozymes PKAmyt1 and PKAmyt2
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Source Tissue

Source Tissue Comment Organism Textmining
digestive gland isozyme PKAmyt1 is the main isoform in the digestive tract Mytilus galloprovincialis
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gill filament only isoform PKAmyt1 is detected in the cytoplasm of the lateral, frontolateral and frontal ciliated cells of the frontal face, and the cytoplasm of the non-ciliated cells and the mucous cells of the abfrontal face. Conversely, only the PKAmyt2 isozyme occurs in the cilia of lateral, frontolateral and frontal cells Mytilus galloprovincialis
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hemocyte
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Mytilus galloprovincialis
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hemolymph vessel containing numerous hemocytes Mytilus galloprovincialis
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labial palp isozymes PKAmyt1 and PKAmyt2, subunit Rmyt1 is slightly expressed in the cytoplasm of the columnar epithelial cells of the plicated face, whereas subunit Rmyt2 is highly expressed in the cilia Mytilus galloprovincialis
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molluscan catch muscle isoform PKAmyt1 is uniformly distributed along the muscle fibers of either ABRM or PAM, whereas isoform PKAmyt2 is localized only in the periphery of the muscle fibers of ABRM and PAM Mytilus galloprovincialis
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additional information differential distribution of cAMP-dependent protein kinase isoforms in various tissues of the bivalve mollusc, Rmyt1 is uniformly distributed in the cytoplasm of most cell types, whereas Rmyt2 is localized only in the cell periphery and associated with certain cellular structures, such as the cilia of labial palps and gill filaments, overview. Only Rmyt2 is found in the subepithelial connective tissue and the periphery of the vacuolated cells Mytilus galloprovincialis
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mucous gland
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Mytilus galloprovincialis
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Subunits

Subunits Comment Organism
More two PKA isoforms that differ at their regulatory subunit, namely, Rmyt1 or Rmyt2< Mytilus galloprovincialis

General Information

General Information Comment Organism
physiological function PKAmyt2 isozyme might mediate the effects of cAMP on the ciliary beat frequency Mytilus galloprovincialis