Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-p-chloro-phenylthio-cAMP | 0.1 mM activates | Mus musculus | |
forskolin | 0.05 mM activates | Mus musculus | |
IBMX | 0.5 mM activates | Mus musculus | |
additional information | not activated by 8-(4-chlorophenylthio)-2'-O-methyl-cAMP | Mus musculus | |
N6-benzoyl-cAMP | 0.1 mM activates | Mus musculus | |
N6-Monobutyryl-cAMP | 0.1 mM activates | Mus musculus |
Application | Comment | Organism |
---|---|---|
medicine | cAMP-dependent protein kinase acts synergistically with exchange protein directly activated by cAMP to promote adipogenesis | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
H-89 | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3-L1 cell | - |
Mus musculus | - |
adipocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + cAMP-responsive element-binding protein | - |
Mus musculus | ADP + phosphorylated cAMP-responsive element-binding protein | - |
? | |
ATP + Kemptide | - |
Mus musculus | ADP + Kemptide phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKA | - |
Mus musculus |
protein kinase A | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus | |
cAMP | dependent | Mus musculus |