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Literature summary for 2.7.11.11 extracted from

  • Mukai, A.; Hashimoto, N.
    Localized cyclic AMP-dependent protein kinase activity is required for myogenic cell fusion (2008), Exp. Cell Res., 314, 387-397.
    View publication on PubMed
Search for more literature for 2.7.11.11

Activating Compound

Activating Compound Comment Organism Structure
forskolin 0.024 mM, forskolin enhances lamellipodium formation where active PKA is accumulated Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
H-89
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
lamellipodium
-
 Mus musculus 30027
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
COM-3 cell
-
 Mus musculus
-
myoblast
-
 Mus musculus
-
myoblast cell line
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information localized PKA activity is required for fusion of mononucleated myoblasts and plays a pivotal role in the early steps of myogenic cell fusion Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
PKA
-
 Mus musculus
protein kinase A
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus
cAMP dependent Mus musculus