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Literature summary for 2.7.11.11 extracted from

  • Tabish, M.; Clegg, R.A.; Turner, P.C.; Jonczy, J.; Rees, H.H.; Fisher, M.J.
    Molecular characterisation of cAMP-dependent protein kinase (PK-A) catalytic subunit isoforms in the male tick, Amblyomma hebraeum (2006), Mol. Biochem. Parasitol., 150, 330-339.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination of three isozymes resulting from alternative 5'-splicing Amblyomma hebraeum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40600
-
x * 40600, isozyme C1, x * 48200, isozyme C2, x * 52500, isozyme C3 Amblyomma hebraeum
48200
-
x * 40600, isozyme C1, x * 48200, isozyme C2, x * 52500, isozyme C3 Amblyomma hebraeum
52500
-
x * 40600, isozyme C1, x * 48200, isozyme C2, x * 52500, isozyme C3 Amblyomma hebraeum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Amblyomma hebraeum the enzyme plays a central role in regulation of diverse aspects of cellular activity, especially in the controlling of maturation of spermatids ?
-
?

Organism

Organism UniProt Comment Textmining
Amblyomma hebraeum
-
male ticks, three isozymes
-

Posttranslational Modification

Posttranslational Modification Comment Organism
lipoprotein isozyme C1 cotains a consensus sequence for N-myristoylation Amblyomma hebraeum

Source Tissue

Source Tissue Comment Organism Textmining
malpighian tubule
-
Amblyomma hebraeum
-
midgut
-
Amblyomma hebraeum
-
additional information ubiquitous expression of all three isozymes with isozyme C1 showing the highst expression levels in all tissues Amblyomma hebraeum
-
salivary gland
-
Amblyomma hebraeum
-
spermatid immature Amblyomma hebraeum
-
testis
-
Amblyomma hebraeum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme plays a central role in regulation of diverse aspects of cellular activity, especially in the controlling of maturation of spermatids Amblyomma hebraeum ?
-
?

Subunits

Subunits Comment Organism
? x * 40600, isozyme C1, x * 48200, isozyme C2, x * 52500, isozyme C3 Amblyomma hebraeum

Synonyms

Synonyms Comment Organism
PK-A
-
Amblyomma hebraeum
protein kinase A
-
Amblyomma hebraeum