Literature summary for 2.7.11.11 extracted from

Kim, C.; Xuong, N.H.; Taylor, S.S.
Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA (2005), Science, 307, 690-696.

Search for more literature for 2.7.11.11

Activating Compound

Activating Compound	Comment	Organism	Structure
cAMP	dependent on, structural basis of activation mechanism, binding induces conformational changes in the regulatory subunit RIalpha	Mus musculus

Crystallization (Commentary)

Crystallization (Comment)	Organism
complex between the catalytic subunit and a deletion mutant regulatory subunit RIalpha comprising residues 91-244, structure determination and analysis	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
IP20	peptide RRNAI, derived from the inhibitory sequence of RIalpha comprising residues 94-98, inhibition mechanism	Mus musculus
additional information	molecular mechanism of enzyme inhibition by binding of catalytic and regulatory subunits via extended surface of subunit C, overview	Mus musculus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	-	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Subunits

Subunits	Comment	Organism
More	structure of subunit C, subunit R, the cAMP binding site, and the activation loop, interaction sites, overview	Mus musculus

Synonyms

Synonyms	Comment	Organism
PKA	-	Mus musculus

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Mus musculus

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Release 2023.1 (January 2023)