Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cAMP | dependent on | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | substrate ezrin is localized at the cytoskeleton of the apical plasma membrane | Oryctolagus cuniculus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Oryctolagus cuniculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ezrin | Oryctolagus cuniculus | recombinant GST-tagged wild-type ezrin transiently expressed in primary gastric parietal cells from stomach, recombinant mutant S66A and S66D ezrin proteins are no substrates, phosphorylation of ezrin leads to activation of parietal cells required for dilation of apical vacuolar membrane and histamine-stimulated acid secretion in gastric mucosa, overview | ADP + phosphoezrin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
New Zealand white rabbits | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gastric gland | - |
Oryctolagus cuniculus | - |
mucosa | gastric | Oryctolagus cuniculus | - |
stomach | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ezrin | recombinant GST-tagged wild-type ezrin transiently expressed in primary gastric parietal cells from stomach, recombinant mutant S66A and S66D ezrin proteins are no substrates, phosphorylation of ezrin leads to activation of parietal cells required for dilation of apical vacuolar membrane and histamine-stimulated acid secretion in gastric mucosa, overview | Oryctolagus cuniculus | ADP + phosphoezrin | - |
? | |
ATP + ezrin | phosphorylation at Ser66, catalytic subunit of PKA | Oryctolagus cuniculus | ADP + phosphoezrin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKA | - |
Oryctolagus cuniculus |
protein kinase A | - |
Oryctolagus cuniculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Oryctolagus cuniculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Oryctolagus cuniculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Oryctolagus cuniculus |