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Literature summary for 2.7.11.11 extracted from
- The specificities of protein kinase inhibitors: an update (2003), Biochem. J., 371, 199-204.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cAMP | dependent on | Bos taurus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alsterpaullone | 21% inhibition of CDK2 at 0.01 mM | Bos taurus | |
| indirubin-3'-monoxime | 20% inhibition of CDK2 at 0.01 mM | Bos taurus | |
| additional information | no inhibition of CDK2 by kenpaullone | Bos taurus | |
| purvalanol | 18% inhibition of CDK2 at 0.01 mM | Bos taurus | |
| roscovitine | 7% inhibition of CDK2 at 0.01 mM | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
female | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PKA | - |
Bos taurus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 21 | - |
assay at room temperature | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Bos taurus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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