Protein Variants | Comment | Organism |
---|---|---|
C99S | the mutation partially abolishes (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol-induced cell growth inhibition and enhances expression of death receptors 5 and 6 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol | the compound directly binds to the ATP binding site of the enzyme with a strong binding affinity | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [IkappaB protein] | Homo sapiens | - |
ADP + [IkappaB phosphoprotein] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O14920 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
CCD-18Co cell | - |
Homo sapiens | - |
colorectal cancer cell | - |
Homo sapiens | - |
HCT-116 cell | - |
Homo sapiens | - |
SW-480 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [IkappaB protein] | - |
Homo sapiens | ADP + [IkappaB phosphoprotein] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IkappaB kinase beta | - |
Homo sapiens |
IKKbeta | - |
Homo sapiens |