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Literature summary for 2.7.11.10 extracted from

  • DiDonato, J.A.; Hayakawa, M.; Rothwarf, D.M.; Zandi, E.; Karin, M.
    A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB (1997), Nature, 388, 548-554.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein Homo sapiens phosphorylation of IkappaBs marks them out for destruction, thereby relieving their inhibitory effect on NF-kappaB ADP + a phosphoprotein
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Organism

Organism UniProt Comment Textmining
Homo sapiens O15111
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein phosphorylation of IkappaBs marks them out for destruction, thereby relieving their inhibitory effect on NF-kappaB Homo sapiens ADP + a phosphoprotein
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?

Synonyms

Synonyms Comment Organism
inhibitor of nuclear factor kappa B kinase beta subunit inhibitor of nuclear factor kappa-B kinase alpha subunit
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Homo sapiens