Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Zea mays |
Crystallization (Comment) | Organism |
---|---|
crystallized by vapour diffusion method. Crystal structure, at 2.1 A resolution, of recombinant alpha subunit of protein kinase CK2a in the presence of ATP and Mg2+, shows the enzyme in an active conformation stabilized by interactions of the N-terminal region with the activation segment and with a cluster of basic residues known as the substrate recognition site. The active centre is occupied by a partially disordered ATP molecule with the adenine base attached to a novel binding site of low specificity. This finding explains the observation that CK2, unlike other protein kinases, can use both ATP and GTP as phosphorylating agents | Zea mays |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Zea mays | P28523 | casein kinase II subunit alpha | - |
Purification (Comment) | Organism |
---|---|
- |
Zea mays |
Synonyms | Comment | Organism |
---|---|---|
CK2 | - |
Zea mays |