Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.1 extracted from

  • Li, L.F.; Liao, S.K.; Huang, C.C.; Hung, M.J.; Quinn, D.A.
    Serine/threonine kinase-protein kinase B and extracellular signal-regulated kinase regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute lung injury: a prospective, controlled animal experiment (2008), Crit. Care, 12, R103.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.1

Application

Application Comment Organism
medicine high-tidal-volume ventilation induced microvascular permeability, lung fibrosis, and chemokine production are dependent, in part, on activation of the Akt and ERK1/2 pathways Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information serine/threonine kinase-protein kinase B (Akt) and extracellular signal-regulated kinase (ERK1/2) regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute lung injury. High-tidal volume ventilation-induced lung fibrosis is attenuated in Akt deficient mice and in mice with pharmacologic inhibition of ERK1/2 activity by PD98059 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q60823
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
AKT
-
 Mus musculus
serine-threonine kinase B
-
 Mus musculus