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Literature summary for 2.7.11.1 extracted from

  • Murakami, H.; Okayama, H.
    A kinase from fission yeast responsible for blocking mitosis in S phase (1995), Nature, 374, 817-819.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Schizosaccharomyces pombe the enzyme is a key component of the DNA replication-monitoring S/G2 checkpoint system. Its primary role is to monitor DNA synthesis by interacting with DNA polymerase alpha and send a signal to block the onset of mitosis while DNA synthesis is in progress ?
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Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe Q09170
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is a key component of the DNA replication-monitoring S/G2 checkpoint system. Its primary role is to monitor DNA synthesis by interacting with DNA polymerase alpha and send a signal to block the onset of mitosis while DNA synthesis is in progress Schizosaccharomyces pombe ?
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?

Synonyms

Synonyms Comment Organism
protein kinase cds1
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Schizosaccharomyces pombe