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Literature summary for 2.7.10.2 extracted from
- Porcine sperm capacitation and tyrosine kinase activity are dependent on bicarbonate and calcium but protein tyrosine phosphorylation is only associated with calcium (2003), Biol. Reprod., 68, 207-213.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| bistyrphostin | complete inhibition of TK-32 | Sus scrofa |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| bicarbonate | required by TK-32 for sperm capacitation activity | Sus scrofa | |
| Ca2+ | required by TK-32 for tyrosine phosphorylation and sperm capacitation activities | Sus scrofa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
x * 32000, SDS-PAGE | Sus scrofa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + p32-L-tyrosine | Sus scrofa | - |
ADP + p32-L-tyrosine phosphate | - |
? | |
| additional information | Sus scrofa | the enzyme is involved in regulation of sperm capacitation, signal transduction mechanism, capacitation mechanism, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| sperm | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + p32-L-tyrosine | - |
Sus scrofa | ADP + p32-L-tyrosine phosphate | - |
? | |
| ATP + p32-L-tyrosine | p32 is a sperm protein | Sus scrofa | ADP + p32-L-tyrosine phosphate | - |
? | |
| additional information | the enzyme is involved in regulation of sperm capacitation, signal transduction mechanism, capacitation mechanism, overview | Sus scrofa | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 32000, SDS-PAGE | Sus scrofa |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TK-32 | - |
Sus scrofa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Sus scrofa | |
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Release 2023.1 (January 2023)
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