Literature summary for 2.7.10.2 extracted from

Attisano, L.; Wrana, J.L.; Cheifetz, S.; Massague, J.
Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors (1992), Cell, 68, 97-108.

Search for more literature for 2.7.10.2

Cloned(Commentary)

Cloned (Comment)	Organism
four new activin receptor isoforms	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Mus musculus	16020	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P27040	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
additional information	two of the ActR-IIB isoforms have higher affinity for activin A than the previously cloned activin receptor and differ from each other by the inclusion of an alternatively spliced segment in the cytoplasmic juxtamembrane region. A second alternative splicing event generates two additional receptor isoforms that lack a proline cluster in the external juxtamembrane region and have lower affinity for activin A	Mus musculus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	all isoforms of the activin receptor type II bind inhibin A with low affinity	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
activin receptor type IIB	-	Mus musculus
ACTR-IIB	-	Mus musculus

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Release 2023.1 (January 2023)