Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protein tyrosine | Homo sapiens | p135tyk2 tyrosine kinase directly binds and tyrosine phosphorylates alpha subunit of the type I IFN receptor, IFN-R | ADP + protein tyrosine phosphate | - |
? | |
additional information | Homo sapiens | p135tyk2 tyrosine kinase directly binds and tyrosine phosphorylates alpha subunit of the type I IFN receptor, IFN-R. Tyk2 protein functions as part of a receptor complex to initiate intracellular signaling in response to type I interferons | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P29597 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protein tyrosine | p135tyk2 tyrosine kinase directly binds and tyrosine phosphorylates alpha subunit of the type I IFN receptor, IFN-R | Homo sapiens | ADP + protein tyrosine phosphate | - |
? | |
additional information | p135tyk2 tyrosine kinase directly binds and tyrosine phosphorylates alpha subunit of the type I IFN receptor, IFN-R. Tyk2 protein functions as part of a receptor complex to initiate intracellular signaling in response to type I interferons | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
non-receptor tyrosine-protein kinase TYK2 | - |
Homo sapiens |
p135tyk2 tyrosine kinase | - |
Homo sapiens |