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Literature summary for 2.7.10.2 extracted from

  • Quintrell, N.; Lebo, R.; Varmus, H.; Bishop, J.M.; Pettenati, M.J.; Le Beau, M.M.; Diaz, M.O.; Rowley, J.D.
    Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells (1987), Mol. Cell. Biol., 7, 2267-2275.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.2

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane likely to be a peripheral membrane protein Homo sapiens 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme may serve specialized functions in hemopoietic cells, it is possible that damage to HCK may contribute to the pathogenesis of some human leukemias ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P08631
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Source Tissue

Source Tissue Comment Organism Textmining
hematopoietic cell expression is prominent in the lymphoid and myeloid lineages of hemopoiesis. Expression in granulocytic and monocytic leukemia cells increases after the cells have been induced to differentiate Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme may serve specialized functions in hemopoietic cells, it is possible that damage to HCK may contribute to the pathogenesis of some human leukemias Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
tyrosine-protein kinase HCK
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 Homo sapiens