Literature summary for 2.7.10.1 extracted from

Nevo, O.; Many, A.; Xu, J.; Kingdom, J.; Piccoli, E.; Zamudio, S.; Post, M.; Bocking, A.; Todros, T.; Caniggia, I.
Placental expression of soluble fms-like tyrosine kinase 1 is increased in singletons and twin pregnancies with intrauterine growth restriction (2008), J. Clin. Endocrinol. Metab., 93, 285-292.

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Application

Application	Comment	Organism
medicine	differential sFlt-1 expression in placentas from discordant twins. sFlt-1 expression is increased in severe intrauterine growth restriction placentas with abnormal umbilical artery Doppler of singletons and also in discordant intrauterine growth restriction twins. Reduced placental perfusion may contribute to the increased expression of sFlt-1 in intrauterine growth restriction pregnancies	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	expression of sFlt-1 mRNA and protein is significantly increased in intrauterine growth restriction placentas compared with small for gestational age and normal control placentas. sFlt-1 expression levels are also significantly greater in the small intrauterine growth restriction twin placentas from discordant twin pregnancies compared with the normal cotwin. In preeclamptic twins, sFlt-1 expression is increased in only one of the two placentas examined	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
sFlt-1	-	Homo sapiens
soluble fms-like tyrosine kinase 1	-	Homo sapiens

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Release 2023.1 (January 2023)