Literature summary for 2.7.10.1 extracted from

Vazquez-Martin, A.; Ortega-Delgado, F.J.; Fernandez-Real, J.M.; Menendez, J.A.
The tyrosine kinase receptor HER2 (erbB-2): From oncogenesis to adipogenesis (2008), J. Cell. Biochem., 105, 1147-1152.

Search for more literature for 2.7.10.1

Application

Application	Comment	Organism
medicine	non-oncogenic role for HER2 in the process of adipose differentiation and HER2 may represent a previously unrecognized target to manage obesity via the lipogenic enzyme FASN	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	cytoplasmic expression of HER2 significantly augments during the differentiation of preadipocytes	Mus musculus	5737	-
plasma membrane	cell membrane-associated expression of HER2 significantly augments during the differentiation of preadipocytes	Mus musculus	5886	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P70424	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
3T3-L1 cell	HER2 is absent in undifferentiated cultures of adipocytes, not subjected to hormonal treatment but processed at the same time as the differentiating cultures from day 0 to day 14. Expression of HER2 significantly augments during the differentiation of preadipocytes. HER2 acculmulation reaches a maximum at day 9	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
ErbB-2	-	Mus musculus
HER2	-	Mus musculus
tyrosine kinase receptor HER2	-	Mus musculus

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Release 2023.1 (January 2023)