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Literature summary for 2.7.10.1 extracted from

  • Delalande, J.M.; Barlow, A.J.; Thomas, A.J.; Wallace, A.S.; Thapar, N.; Erickson, C.A.; Burns, A.J.
    The receptor tyrosine kinase RET regulates hindgut colonization by sacral neural crest cells (2008), Dev. Biol., 313, 279-292.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information overexpression of RET by electroporation in sacral neural crest cells, increases their ability to colonize the hindgut Homo sapiens

Application

Application Comment Organism
additional information RET is a cell-intrinsic marker that regulates hindgut colonization by sacral neural crest cells, and has the ability to promote the enteric nervous system developmental potential of sacral neural crest cells towards that of vagal neural crest cells Gallus gallus
additional information RET is a cell-intrinsic marker that regulates hindgut colonization by sacral neural crest cells, and has the ability to promote the enteric nervous system developmental potential of sacral neural crest cells towards that of vagal neural crest cells Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of RET in sacral neural crest cells by electroporating RET into the sacral neural tube of quail embryos and heterotopically grafting into vagal neural crest cell-ablated chick embryos at the same stage of development Homo sapiens

Organism

Organism UniProt Comment Textmining
Gallus gallus
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-
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Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
hindgut
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Gallus gallus
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neural crest 4fold increase in expression in vagal versus sacral neural crest cells Gallus gallus
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Synonyms

Synonyms Comment Organism
receptor tyrosine kinase RET
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Gallus gallus
receptor tyrosine kinase RET
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Homo sapiens