Literature summary for 2.7.1.91 extracted from

Kim, H.L.; Sacket, S.J.; Han, M.; Im, D.S.
Characterization of N,N,-dimethyl-D-erythro-sphingosine-induced apoptosis and signaling in U937 cells: independence of sphingosine kinase inhibition (2008), Prostaglandins Other Lipid Mediat., 86, 18-25.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
U-937 cell	N,N-dimethyl-D-erythro-sphingosine induces apoptotic cell death via modulation of mitochondrial membrane potential, c-Jun N-terminal protein kinase, p38 MAP kinase, extracellular signal-regulated kinase, and Akt kinase, but not through inhibition of sphingosine kinase or protein -kinase C in U937 cells	Homo sapiens	-

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Release 2023.1 (January 2023)