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Literature summary for 2.7.1.86 extracted from
- A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae (2003), EMBO J., 22, 2015-2024.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression in Escherichia coli | Saccharomyces cerevisiae |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + NADH | Saccharomyces cerevisiae | the enzyme has primarily NADH kinase activity in mitochondria, mitochondrial NADPH is largely provided by the POS5 NADH kinase | ADP + NADPH | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + NAD+ | activity with NAD+ is 50fold lower than with NADH | Saccharomyces cerevisiae | ADP + NADP+ | - |
? | |
| ATP + NADH | - |
Saccharomyces cerevisiae | ADP + NADPH | - |
? | |
| ATP + NADH | the enzyme has primarily NADH kinase activity in mitochondria, mitochondrial NADPH is largely provided by the POS5 NADH kinase | Saccharomyces cerevisiae | ADP + NADPH | - |
? | |
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Release 2023.1 (January 2023)
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